Brain Perfusion and Vasoreactivity in Multiple Sclerosis
نویسندگان
چکیده
منابع مشابه
Brain perfusion and vasoreactivity in multiple sclerosis.
Multiple sclerosis (MS) is a chronic disorder of the central nervous system, pathologically characterized by inflammation, demyelination, and neurodegeneration. In past years, there has been increasing attention paid to its ischemicvascular aspects because abnormalities in CBF and CBV have been consistently described in both WM and GM, in all MS stages. The enhanced expression of an hypoxia-ind...
متن کاملAbnormalities of cerebral perfusion in multiple sclerosis.
BACKGROUND Measuring perfusion provides a potential indication of metabolic activity in brain tissue. Studies in multiple sclerosis (MS) have identified areas of decreased perfusion in grey matter (GM) and white matter (WM), but the pattern in clinical subgroups is unclear. OBJECTIVES This study investigated perfusion changes in differing MS clinical subgroups on or off beta-interferon therap...
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The proximity of immune cell aggregations to the vasculature is a hallmark of multiple sclerosis. Furthermore, it is widely accepted that inflammation is able to modulate the microcirculation. Until recently, the detection of cerebral blood perfusion changes was technically challenging, and perfusion studies in multiple sclerosis patients yielded contradictory results. However, new developments...
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Background: Identifying the predictors of pain is important for both health professionals and researchers, because pain has repeatedly been found to be a strong predictor of activity limitations and participation restrictions. The objective of this study was to determine the predictors of pain presence and severity in a large, well-designed sample of community dwelling individuals with multip...
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Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system (CNS). This highlydisabling disorder is characterized by a variable clinical course. MS is a heterogeneous disease with acomplex pathology and significant social and economic impact. MS is associated with dysfunction ofparts of the nervous system which results in a range of signs and symptoms, ...
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ژورنال
عنوان ژورنال: American Journal of Neuroradiology
سال: 2015
ISSN: 0195-6108,1936-959X
DOI: 10.3174/ajnr.a4249